| 学术论文： |
• 计算机科学会议论文 (conference paper)
[1]. S. Xu, S. Zou and L. Wang A Geometric Clustering Algorithm and Its Applications to Structural Data. (RECOMB2014) (acceptance rate 16.7%, RECOMB is one of the most prestigious conferences in computational biology and bioinformatics).
[2]. L. Wang (2010) The Geometric and Electrostatic Properties of Binding Cavities and Their Usage in Protein-Ligand Docking. Frontier of Computer Science and Technology, Changchun, China (August 2010) pp. 442–447.
[3]. L. Wang and B. R. Donald (2006) A Data-Driven, Systematic Search Algorithm for Structure Determination of Denatured or Disordered Proteins. The Computational Systems Bioinformatics Conference (CSB), Stanford CA (August, 2006) pp. 67–78 (Best Paper Award)。
[4]. L. Wang and B. R. Donald (2005). An Efficient and Accurate Algorithm for Assigning Nuclear Overhauser Effect Restraints Using a Rotamer Library Ensemble and Residual Dipolar Couplings. IEEE Computer Society Bioinformatics Conference (CSB2005), Stanford CA (August, 2005) pp. 189–202。
[5]. L. Wang, R. Mettu and B. R. Donald (2005). An Algebraic Geometry Approach to Backbone Structure Determination from NMR Data. IEEE Computer Society Bioinformatics Conference. IEEE Computer Society Bioinformatics Conference (CSB2005) Stanford CA (August, 2005) pp. 235–246。
[6]. L. Wang and B. R. Donald (2004). Analysis of a Systematic Search-Based Algorithm for Determining Protein Backbone Structure from a Minimal Number of Residual Dipolar Couplings. The IEEE Computational Systems Bioinformatics Conference (CSB2004), Stanford CA (August, 2004) pp. 319-330。
[7]. C. Langmead, A. Yan, R. Lilien, L. Wang and B. R. Donald (2003). A Polynomial-Time Nuclear Vector Replacement Algorithm for Automated NMR Resonance Assignments. Proceedings of the Seventh Annual InternationalConference on Research in Computational Molecular Biology (RECOMB2003), 176-187. Berlin, Germany, April 10-13。
[8]. L. Wang, R. Mettu, R. Lilien and B. R. Donald (2003). An Exact Algorithm for Determining Protein Backbone Structure from NH Residual Dipolar Couplings. IEEE Computer Society Bioinformatics Conference (CSB2003), 611-612. Stanford, CA, August 11-14. (Best Poster Award)。
• 杂志论文 （生物化学，生物物理，结构生物学和计算机科学）
[1]. L. Wang, Y, Hou, H. Quan, W. Xu, Y. Bao, Y. Li, Y. Fu, S. Zou (2013) A Compound-Based Computational Approach for the Accurate Determination of Hot Spots. Protein Science 22(8):1060-70.
[2]. X. Y. Yuan, D. Y. Fu, X. F. Ren, X. Fang, L. Wang, S. Zou, and Y. Wu (2013) Highly Selective Aza-nitrile Inhibitors for Cathepsin K, Structural Optimization and Molecular Modeling. Org. Biomol. Chem. 11(35):5847-5.
[3]. X. F. Ren, H, W. Li, X. Fang, Y. Wu, L. Wang, and S. Zou (2013) Highly Selective Azadipeptide Nitrile Inhibitors for cathepsin K: Design, Synthesis and Activity Assays. Org. Biomol. Chem. 11(7):43-8.
[4]. L. Wang, S. Zou, and Y. Wang (2012) Algorithmic challenges in structure-based drug design and NMR structural biology. Front. Electr. Electron. Eng. 7(1):69-84.
[5]. J. Zeng, J. Boyles, C. Tripathy, L. Wang, A. Yan, P. Zhou, and B. R. Donald (2009) High-Resolution Protein Structure Determination Starting with a Global Fold Calculated from Exact Solution to the RDC Equations. J. Biomol. NMR, 45(3):265-281.
[6]. L. Wang, P. Rossi, C, X. Chen, C. Nwosu, K. Cunningham, L .C. Ma, R. Xiao, J. Liu, M. .C. Baran, G. .T. V. Swapna, T. .B. Acton, R. Burkhard, and G. T. Montelione (2007). Northeast Structural Genomics Consortium Target SiR5 (PDBID 2OA4), RCSB.
[7]. L. Wang, P. Rossi, C. .X. Chen, C. Nwosu, K. Cunningham, L .C. Ma, R. Xiao, J. Liu, M. .C. Baran, G. .T. V. Swapna, T. .B. Acton, R. Burkhard, and G. T. Montelione (2007). Northeast Structural Genomics Consortium Target RHR5 (PDBID 2JRT), RCSB.
[8]. L. Wang and W. Hu (2006) Residual Dipolar Couplings: Measurements and applications to biomolecular studies. Annual Reports on NMR Spectroscopy, 58: 232–304。
[9]. L. Wang, R. Mettu and B. R. Donald (2006). A Polynomial-time Algorithm for De Novo Protein Backbone Structure Determination from NMR Data. Journal of Computational Biology 13(7):1276-1288。
[10]. L. Wang and B. R. Donald (2004) Exact Solutions for Internuclear Vectors and Backbone Dihedral Angles from NH Residual Dipolar Couplings in Two Media, and Their Application in a Systematic Search Algorithm for Determining Protein Backbone Structure. J. Biomol. NMR, 29(3):223–242。
[11]. C. Langmead, A. Yan, R. Lilien, L. Wang and B. R. Donald (2003). A Polynomial-Time Nuclear Vector Replacement Algorithm for Automated NMR Resonance Assignments. Journal of Computational Biology 11(2–3):277–298。
[12]. L. Wang, Y. Pang, T.Holder, J. R. Brender, A. V. Kurochkin, and E. R. P. Zuiderweg (2001) Functional Dynamics in the Active Site of the Ribonuclease Binase. Proceedings of the National Academy of Sciences, USA, 98,7684–7689。
[13]. L. Wang, A. V. Kurochkin and E. R. P. Zuiderweg (2000) An Iterative Fitting Procedure for the Determination of Longitudinal NMR Cross-Correlation Rates. J. Magn. Reson. 144,175-185。
[14]. M. Pellecchia, Y. Pang, L.Wang, A. V. Kurochkin, A. Kumar and E. R. P. Zuiderweg (1999) Quantitative Measurement of Cross-Correlations Between 15N and 13CO Chemical Shift Anisotropy Relaxation Mechanisms by Multiple Quantum NMR. J. Am. Chem. Soc. 121, 9165-9170。
[15]. Y. Pang, L. Wang, M. Pellecchia, A. V. Kurochkin and E. R. P. Zuiderweg (1999) Evidence for Extensive Anisotropic Local Motions in a Small Enzyme Using a New Method to Determine NMR Cross-Correlated Relaxation Rates in the Absence of Resolved Scalar Coupling. J. Biomol. NMR 14(4), 297-306。
[16]. L. Wang and H. Yan (1999) NMR Studies of Type II Human Cellular Retinoic Acid Binding Protein. Biochimica et Biophysica Acta 1433, 240-252。
[17]. L. Wang, Y. Li, F. Abildgaard, J. L. Markley and H. Yan (1998) NMR Solution Structure of Type II Human Cellular Retinoic Acid Binding Protein: Implications for Ligand Binding. Biochemistry 37, 12727-12736。
[18]. L. Wang and H. Yan (1998) NMR Study Suggests a Major Role for Arg111 in Maintaining the Structure and Dynamical Properties of Type II Cellular Retinoic Acid Binding protein. Biochemistry 37. 13021-13032。
[19]. X. Chen, M. Tordova, G. L. Gilliland, L. Wang, Y. Li, H. Yan and X. Ji (1998) Crystal Structure of Cellular Retinoic Acid Binding Protein Type II: Suggestions a Mechanism of Ligand Entry. J. Mol. Biol. 278, 641-653。
[20]. H. Yan, L. Wang and Y. Li (1997) A Novel Method for Measuring the Binding Properties of the Site-Directed Mutants of The Proteins that Binding Hydrophobic Ligands: Application to Cellular Retinoic Acid Binding Proteins. In Techniques in Protein Chemistry VIII (Marshak D. R. Ed.), 449-456. Academic Press, San Diego。
[21]. L. Wang, Y. Li and H. Yan (1997) Human Cellular Retinoic Acid Binding Proteins: Quantitative Analysis of the Ligand Binding Properties of the Wild-Type and Site-Directed Mutants. J. Biol. Chem. 272, 1541-1547。
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